منابع مشابه
The Mpl receptor is expressed in the megakaryocytic lineage from late progenitors to platelets.
The Mpl receptor (Mpl-R) is a cytokine receptor belonging to the hematopoietin receptor superfamily for which a ligand has been recently characterized. To study the lineage distribution of Mpl-R in normal hematopoietic cells, we developed a monoclonal antibody (designated M1 MoAb) by immunizing mice with a soluble form of the human Mpl-R protein. With few exceptions, Mpl-R was detected by indir...
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The Push, the Pull and the Push&Pull algorithms are well-known rumor spreading protocols. In all three, in the beginning one node of a graph is informed. In the Push setting, every round every informed node chooses a neighbor uniformly at random and, if it is not already informed anyway, informs it. In the Pull setting, each round each uninformed node chooses a neighbor uniformly at random and ...
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Biological evolution has struggled to produce mechanisms that can limit blood loss following injury. In humans and other mammals, control of blood loss (hemostasis) is achieved through a combination of plasma proteins, most of which are made in the liver, and platelets, anucleate blood cells that are produced in the bone marrow by megakaryocytes. Much has been learned about the underlying mecha...
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Background: The origin and function of human leukocyte antigen (HLA) class I molecules on platelets are still highly arguable. Given the differences in the results of the previous studies in this regard, the lack of research in recent years, and the clinical importance of HLA class I molecules, the absorption capacity of platelets for soluble HLA class I molecules was studied in this investigat...
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Introduction: It has been reported that platelets can eradicate tumor cells in vitro, although the mechanism of this effect has not been determined. The effect of platelets on the induction of apoptosis in tumor cells is largely unknown. Materials and methods: To investigate this effect, two human hematologic cell lines, K562 and Daudi, were independently faced with unstimulated and thromb...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2006
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.2035iti3